From the perspective of technology and application, this book introduces the optimization method and various analysis techniques on the experiment design and data processing to improve the level of experiment design and the effectiveness of optimization. This book consists of 11 chapters. In addition to introducing the basic principles and common methods, it also introduces the latest methods, research and application examples. It also introduces the common statistical softwares. This book can be used as textbook for science, engineering, agriculture, medicine, economics, management, and other undergraduates. Also it can provide reference for researchers, engineers, designers, experimentalists, marketers and administrators.